ROOTED References

Below are the references used in the ROOTED movie.  All are accessible via Medline.

1 "The Changing Face Of Dentistry - Endodontics" by Dr Paul V. Abbott BDSc, MDS, FRACDS(Endo). Australian Dental Association News Bulletin April 1996

2 J. Guttman et al J. Endo 13:12 1987

3 Stanley H "Pulpal responses to ionomer cements" JADA 1990

4 Samulson H., Sieraski S "diseases of the dental histopathology and pulp" ed/ Franklin S weine endodontic therapy 1989

5 U. Schellenberg et al J. Endo 18:3 1992

6 D. Pashley Clinical Considerations of Microleakage J. Endo 16:2 1990

7 Buck, R. A. DMD; Eleazer, P. D. DDS, MS; Staat, R. H. PhD; Scheetz, J. P. PhD Effectiveness of Three Endodontic Irrigants at Various Tubular Depths in Human Dentin Journal of Endodontics: Volume 27(3) March 2001 pp 206-208

8 I. Bender J. Endo 23:1 1997
One of the most respected root therapy specialists, Dr I. Bender, makes the following statements:

9 Kesel RG a critique of methods in filling root canals. In Grossman LI editor. Transactions of the international conference on endodontics, Philadelphia 1958

10 Kesel RG a critique of methods in filling root canals. In Grossman LI editor. Transactions of the international conference on endodontics, Philadelphia 1958

11 Malcolm Davis . Periapical and Intracanal Healing following incomplete root canal fillings in dogs. Oral surgery may 1971 vol. 31 no 5

12 Australian Dental Association handout December 1996

13 E. Mandel Scanning Electron Microscope Observation of Canal Cleanliness. J. Endo. 16:6 1990

14 Josef Issels MD Cancer A second Opinion 1999 ISBN 0-89529-992-5
"Odontogenic toxins wherever they may have been produced, are able to diffuse and circulate within the organism."

15 Focal Infection - The endodontic point of view Ehrmann Oral Surgery Vol 44 No 4 October 1977

16 Sundqvist, in 1976, isolated 88 species of bacteria from32 root canals with periapical disease.

17 Wu, Moorer, Wesselink. Capacity of anaerobic bacteria enclosed in a simulated root canal to induce inflammation. Int. Endodontic Journal (1989) 22, 269-277

18 Nair PN, Sjogren U, Krey G, Kahnberg KE, Sundqvist G J Endod 1990 Dec;16(12):580-588 Intraradicular bacteria and fungi in root-filled, asymptomatic human teeth with therapy-resistant periapical lesions: a long-term light and electron microscopic follow-up study

19 J. Baumgartner J. Endo. 17:8 August 1991

20 Kobayashi T, Hayashi A, Yoshikawa R, Okuda K, Hara K Niigata Int Endod J 1990 Mar;23(2):100-106 The microbial flora from root canals and periodontal pockets of non-vital teeth associated with advanced periodontitis

21 Kobayashi T, Hayashi A, Yoshikawa R, Okuda K, Hara K Niigata
Ando N, Hoshino E Int Endod J 1990 Jan;23(1):20-27 Predominant obligate anaerobes invading the deep layers of root canal dentin. Ando N, Hoshino E

22 Sundqvist G, Figdor D, Persson S, Sjogren U Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998 Jan;85(1):86-93 Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment

23 Sundqvist G, Figdor D, Persson S, Sjogren U
B Wayman et a. J. Endo 18:4 1992

24 Asikainen S, Alaluusua S Eur Heart J 1993 Dec;14 Suppl K:43-50 Bacteriology of dental infections.
M.K. Wu, Moorer Wesselink Int. Endodontic Journal (1989) 22, 269-277

25 Soekanto et al J. Endo 22:6 1996

26 Dr Weston A Price, Dental Infections - Oral and Systemic 1923

27 Philip Delivanis Oral Surgery 1981 Vol 52 No 4

28 E. Berutti et al J. Endo 23:12 1997Journal of Endodontics: Volume 27(3) March 2001 pp 206-208

29 Buck, R. A. DMD; Eleazer, P. D. DDS, MS; Staat, R. H. PhD; Scheetz, J. P. PhD Effectiveness of Three Endodontic Irrigants at Various Tubular Depths in Human Dentin Journal of Endodontics: Volume 27(3) March 2001 pp 206-208

30 1920 Dr Price
"….not only do we have great difficulty, amounting practically to an impossibility, in completely sterilising tooth structure, but also our efforts may result in the development of a more virulent organism if we have not exterminated the last one."

31 Since the 1920's it has been evident that infections in teeth can seriously effect changes in other organs of the body: ( Weston Price )

32 (http://www.ada.org Jan 2005)

33 Horiba N, Maekawa Y, Matsumoto T, Nakamura H J Endod 1990 Jul;16(7):331-334 A

34 Alves J.A., Barrieshi K, Walton R. E., Wertz P. Wilcox L., Drake D. J Dent Res 1996; 75 (special issue):373 abstract 2847).

35 R. Nissan et al J. Endo 21:2 1995

36 Horiba N, Maekawa Y, Matsumoto T, Nakamura H J Endod 1990 Jul;16(7):331-334 A

37 Schein B J. of Endodontics 1975 Vol 1 No 1 Measurable quantities of endotoxins are found in root filled teeth.

38 Dr. Boyd Haley and Dr. Curt Pendergrass; [Affinity Labeling Technologies, Inc., USA] Bio-Probe journal (Vol 14-5); 1998

39 Penner A et al. J Exp Med 1960;111:145-53

40 Parnas I Science 1971;171:1153-5

41 Alper M Proc Soc Exp Biol Med 1967;124:537-8

42 Palmiro C J Exp Med 1962 ;115:609-12

43 Toxicol Lett 1996 Jan;84(1):43-53 Effects of repeated exposures of hydrogen sulphide on rat hippocampal EEG. Skrajny B, Reiffenstein RJ, Sainsbury RS, Roth SH

44 Can J Physiol Pharmacol 1992 Nov;70(11):1515-1518 Low concentrations of hydrogen sulphide alter monoamine levels in the developing rat central nervous system. Skrajny B, Hannah RS, Roth SH

45 J Neurophysiol 1993 Jul;70(1):81-96 The actions of hydrogen sulfide on dorsal raphe serotonergic neurons in vitro. Kombian SB, Reiffenstein RJ, Colmers WF

46 Toxicol Ind Health 1995 Mar;11(2):185-197 Hydrogen sulfide and reduced-sulfur gases adversely affect neurophysiological functions. Kilburn KH, Warshaw RH

47 Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher J Periodontol 1996 Oct;67(10 Suppl):1123-1137 Periodontal disease and cardiovascular disease

48 Kipioti A, Nakou M, Legakis N, Mitsis F Oral Surg Oral Med Oral Pathol 1984 Aug;58(2):213-220 Microbiological findings of infected root canals and adjacent periodontal pockets in teeth with advanced periodontitis.

49 Kerekes K, Olsen I Endod Dent Traumatol 1990 Feb;6(1):1-5 Similarities in the microfloras of root canals and deep periodontal pockets.

50 Asikainen S, Alaluusua S Eur Heart J 1993 Dec;14 Suppl K:43-50 Bacteriology of dental infections.

51 M.K. Wu, Moorer Wesselink Int. Endodontic Journal (1989) 22, 269-277
Schein B J. of Endodontics 1975 Vol 1 No 1

52 Asikainen S, Alaluusua S Eur Heart J 1993 Dec;14 Suppl K:43-50 Bacteriology of dental infections.

53 M.K. Wu, Moorer Wesselink Int. Endodontic Journal (1989) 22, 269-277

54 Schein B J. of Endodontics 1975 Vol 1 No 1

55 Horiba N, Maekawa Y, Matsumoto T, Nakamura H J Endod 1990 Jul;16(7):331-334

56 A study of the distribution of endotoxin in the dentinal wall of infected root canals.
Horiba et al. Oral Surg. Oral Med. Oral Path. 1991 Vol 71

57 J Neurophysiol 1993 Jul;70(1):81-96 The actions of hydrogen sulfide on dorsal raphe serotonergic neurons in vitro. Kombian SB, Reiffenstein RJ, Colmers WF

58 Toxicol Ind Health 1995 Mar;11(2):185-197 Hydrogen sulfide and reduced-sulfur gases adversely affect neurophysiological functions. Kilburn KH, Warshaw RH

59 Annu Rev Pharmacol Toxicol 1992;32:109-134 Toxicology of hydrogen sulfide. Reiffenstein RJ, Hulbert WC, Roth SH

60 J Appl Physiol 1995 Feb;78(2):433-440 Sulfide-induced perturbations of the neuronal mechanisms controlling breathing in rats. Greer JJ, Reiffenstein RJ, Almeida AF, Carter JE

61 Malcolm Davis . Periapical and Intracanal Healing following incomplete root canal fillings in dogs. Oral surgery may 1971 vol. 31 no 5

62 C. Budd J.Endo 17:6 1991

63 F. Goldberg et al J. Endo 21:1 1995

64 J. Simons et al J. Endo 17:3 1991

65 Journal of Endodontics: Volume 26(1) January 2000 pp 29-31

66 Saliva penetration of filled root canals was considered to be clinically significant
M. Magura J. Endo 17:7 1991

67 Leakage of Amalgam, Composite, and Super-EBA, Compared with a New Retrofill Material: Bone Cement Holt, Gary Matthew BS; Dumsha, Thom C. DDS, MS

68 Chong BS Pitt Ford TR Watson TF Wilson RF Sealing ability of potential retrograde root filling materials. Endod Dent Traumatol (1995 Dec) 11(6):264-9

69 Adamo HL Buruiana R Schertzer L Boylan RJ A comparison of MTA, Super-EBA, composite and amalgam as root-end filling materials using a bacterial microleakage model. Int Endod J (1999 May) 32(3):197-203

70 Higa RK Torabinejad M McKendry DJ McMillan PJ The effect of storage time on the degree of dye leakage of root-end filling materials. Int Endod J (1994 Sep) 27(5):252-6

71 Peters LB Harrison JW A comparison of leakage of filling materials in demineralized and non- demineralized resected root ends under vacuum and non-vacuum conditions. Int Endod J (1992 Nov) 25(6):273-8

72 Ayhan H Alacam A Olmez A Apical microleakage of primary teeth root canal filling materials by clearing technique. J Clin Pediatr Dent (1996 Winter) 20(2):113-7

73 Yatsushiro JD Baumgartner JC Tinkle JS Longitudinal study of the microleakage of two root-end filling materials using a fluid conductive system. J Endod (1998 Nov) 24(11):716-9

74 Wu MK Kontakiotis EG Wesselink PR Long-term seal provided by some root-end filling materials. J Endod (1998 Aug) 24(8):557-60

75 Torabinejad M Higa RK McKendry DJ Pitt Ford TR Dye leakage of four root end filling materials: effects of blood contamination. J Endod (1994 Apr) 20(4):159-63

76 Fogel BB A comparative study of five materials for use in filling root canal spaces. Oral Surg Oral Med Oral Pathol (1977 Feb) 43(2):284-99

77 Tollens H [Root canal filling materials (electron scanning microscope comparison of root canal adaptation to 3 endodontic filling products) Rev Belge Med Dent (1979) 34(4):351-84

78 (http://www.aae.org)

79 Stortebecker P "Dental Infectious Foci and diseases of the nervous system - spread of microorganisms and their products from dental infectious foci along direct cranial venous pathways eliciting a toxic - infectious encephalopathy" Acta. Psych Neural Scand 36 Suppl. 157 (1961) 62

80 Stortebecker P "The cranial venous system filled from pulp of a tooth - Proceedings" 3rd Int. Congress of Nero Surg. Copenhagen Aug 1965

81 Stortebecker P "Dental significance of pathways for dissemination from infectious foci." J Can Dent Assoc 33:6 1967 pp301-311

82 Stortebecker P "Chronic dental infections in the etiology of Glioblastomas. 8th int congress" Neuropathy. Washington D.C. Sept 1978 J Neuropth. Exp. Neurology 37(s) 1978

83 E. Pascon In Vitro Cytotoxicity of root canal filling materials. J. Endo. Vol 16 No 9 1990

84 In 1995, Economedes studied four different root filling cements. They are amongst the most popular used at present - AH-26, Roth 811, CRCS, Sealapex all caused mild to severe tissue irritation;
Roth 811, CRCS induced zinc redistribution to different organs (liver, kidney, uterus, brain;
AH-26 (induced changes in Ca content in some organs).


Economedes showed that zinc was distributed from root canals filled with CRCS and Roth 811. High levels were found in the brain, kidney, liver and uterus.

85 Journal of Endodontics: Volume 26(6) June 2000 pp 321-324 The Mutagenic Potential of AH+ and AH26 by Salmonella/Microsome Assay Jukiç, Silvana DDS; Miletiç, Ivana DDS; Aniç, Ivica DDS, PhD; Britviç, Smiljana PhD; Osmak, Maja PhD; Sistig, Suzana DDS

86 Neurotoxic effects of root filling materials on rat phrenic nerve in vitro. Brodin P Roed A Aars H Orstavik D [J Dent Res (1982 Aug) 61(8):1020-3 ]

87 Comparative neurotoxic effects of root canal filling materials on rat sciatic nerve. Serper A Ucer O Onur R Etikan I [J Endod (1998 Sep) 24(9):592-4 ]

88 Bengtsson, Ulf [Dental Materials In Endodontic Praxis. Ed 1.]
LiTH-IKP-I-137. 1990. http://www.gbg.bonet.se/bwf/art/endoSummary.html

89 Bengtsson, Ulf [Dental Materials In Endodontic Praxis. Ed 1.]
LiTH-IKP-I-137. 1990. http://www.gbg.bonet.se/bwf/art/endoSummary.html

90 Lewis BB Chestner SB Formaldehyde In Dentistry: A Review Of Mutagenic And Carcinogenic Potential J Am Dent Assoc (1981) 103(3):429-434

91 http://www.aesoc.com/

92 B. Briseno J. Endo. 16:8 1990

93 Geurtsen W Leyhausen G Biological aspects of root canal filling materials-- histocompatibility,cytotoxicity, and mutagenicity. Clin Oral Investig (1997 Feb) 1(1):5-11

94 Arenholt-Bindslev D Horsted-Bindslev P A simple model for evaluating relative toxicity of root filling materials in cultures of human oral fibroblasts. Endod Dent Traumatol (1989 Oct) 5(5):219-26

95 Chong BS Owadally ID Pitt Ford TR Wilson RF Cytotoxicity of potential retrograde root-filling materials. Endod Dent Traumatol (1994 Jun) 10(3):129-33

96 Chong BS Ford TR Wilson RF Radiological assessment of the effects of potential root-end filling materials on healing after endodontic surgery. Endod Dent Traumatol (1997 Aug) 13(4):176-9

97 Peltola M Salo T Oikarinen K Toxic effects of various retrograde root filling materials on gingival fibroblasts and rat sarcoma cells. Endod Dent Traumatol (1992 Jun) 8(3):120-4

98 Chong BS Ford TR Kariyawasam SP Tissue response to potential root-end filling materials in infected root canals. Int Endod J (1997 Mar) 30(2):102-14

99 Chong BS Pitt Ford TR Kariyawasam SP Short-term tissue response to potential root-end filling materials in infected root canals. Int Endod J (1997 Jul) 30(4):240-9

100 Pascon EA Spangberg LS In vitro cytotoxicity of root canal filling materials: 1. Gutta- percha. J Endod (1990 Sep) 16(9):429-33

101 Zhu Q Safavi KE Spangberg LS Cytotoxic evaluation of root-end filling materials in cultures of human osteoblast-like cells and periodontal ligament cells. J Endod (1999 Jun) 25(6):410-2

102 Ersev H Schmalz G Bayirli G Schweikl H Cytotoxic and mutagenic potencies of various root canal filling materials in eukaryotic and prokaryotic cells in vitro. J Endod (1999 May) 25(5):359-63

103 R. Gerosa et al J. Endo 21:9 1995

104 Chang, Yu-Chao DDS, MMS; Tai, Kuo-Wei DDS, MSD; Huang, Fu-Mei DDS, MMS; Huang, Ming-Fa DDS, MSD Journal of Endodontics: Volume 26(8) August 2000 pp 462-465

105 In Vitro Cytotoxicity of a New Epoxy Resin Root Canal Sealer Azar, Nasim Gheshlaghi DDS; Heidari, Mahnaz MSc; Bahrami, Zahra Samadi MSc; Shokri, Fazel PhD Journal of Endodontics: Volume 26(9) September 2000 pp 512-516

106 Biocompatibility of Two Current Adhesive Resins de Souza Costa, Carlos Alberto DDS, MS, PhD; Teixeira, Hilcia Mezzalira DDS; Lopes Nascimento, Alexandre Batista do DDS, MS, PhD; Hebling, Josimeri DDS, MS, PhD

107 A 41-yr-old patient experienced an anaphylactic shock reaction caused by formaldehyde in a root canal sealant during endodontic treatment. Journal of Endodontics: Volume 26(9) September 2000 p 529

108 Anaphylactic Shock during Endodontic Treatment due to Allergy to Formaldehyde in a Root Canal Sealant Haïkel, Youssef DCD, DSO, PhD; Braun, Jean Jacques MD; Zana, Hélène MD; Boukari, Abdessamad DCD, DSO; de Blay, Frédéric MD; Pauli, Gaby MD Journal of Endodontics: Volume 26(12) December 2000 pp 703-707

109 Cytotoxicity of Root Canal Filling Materials to Three Different Human Cell Lines Willershausen, Brita Prof. Dr. med. Dent.; Briseño Marroquín, Benjamin Prof. Dr. med. Dent.; Schäfer, Dirk Dipl. Biol.; Schulze, Ralf Dr. med. Dent.

110 Ranly DM Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part one. ASDC J Dent Child (1985 Nov-Dec) 52(6):431-4 ISSN: 0022-0353

111 Capra N. Andersopn KV. Pride JB. Jones TE simultaneous "Demonstration of Neuronal Somata that innovate the tooth pulp and adjacent periodontal tissues using two retrogradely transported anatomic markers." Exp. Neurol 86(1984) 165-170

112 Marfurt C. Turner D 'The central Projections of tooth pulp afferent neurons in the rat as determined by the Transganglionic transport of Horseradish Peroxidase" J. of Comp.Neuro 223 (1984) 535-547.

113 Marfurt C. Turner D Uptake and transneuronal transport of Horseradish Peroxidase - Wheat Germ aglutinin by Tooth Pulp Primary Afferent Neurons' Brain Res. 452(1988) 381-387

11 Arvidson J. Gobel S. "An HRP study of the Central Projections of Primary Trigeminal Neurons which innovate tooth pulps in the cat. Brain Res. 210 (1981) 1-16

115 Kristensson K., Olssan Y., Diffusion Pathways and Retrograde Transport in Peripheral nerves" Prog. In Neurobio. 1 (1973

116 Brodin P Roed A Aars H Orstavik D J Dent Res (1982 Aug) 61(8):1020-3

117 Serper A Ucer O Onur R Etikan I J Endod (1998 Sep) 24(9):592-4

118 Shklar , Person, Ratner. Oral pathology and Trigeminal Neuralgia III J Dent Res. 1976;55(B):299

119 Ratner E., Langer., Evins M., alveolar Cavitational Osteopathosis manifestations of an infectious process and its implications in the causation of chronic pain. J Periodoontal 1986;57:593-603

120 Lewis BB Chestner SB Formaldehyde In Dentistry: A Review Of Mutagenic And Carcinogenic Potential J Am Dent Assoc (1981) 103(3):429-434

121 Hata G. et al. "Systemic distribution of 14 c-labelled Formaldehyde applied in the root Canal following pulpectomy" J. of Endo 15 No11 1989 539-543

122 Ranly DM Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part one. ASDC J Dent Child (1985 Nov-Dec) 52(6):431-4

123 Ranly DM Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part one. ASDC J Dent Child (1985 Nov-Dec) 52(6):431-4

124 Friedberg et al Embryotoxicity and teratogenicity of Formocresol on Developing chick embryos. J. Endo. Vol 16 No 9 1990

125 Avram DC Pulver F Pulpotomy medicaments for vital primary teeth. Surveys to determine use and attitudes in pediatric dental practice and in dental schools throughout the world. ASDC J Dent Child (1989 Nov-Dec) 56(6):426-34

126 P J Waterhouse, J Nunn and J M Whitworth, British Dental Journal VOLUME 188, NO. 1, JANUARY 8 2000

127 Stortebecker, P. Mercury poisoning from dental amalgam through a direct nose-brain transport. The Lancet, May 27, 1989.

128 AK Olson J. Endo 16:8 1990

129 S. Dorn J. Endo 16:8 1990

130 K. King Et Al J. Endo 16:7 1990

131 M. Yoshimura J. Endo 16:1 1990

132 S. Dazey et al J. Endo 16:1 1990

133 C. Nixon et al J. Endo 17:10 1991

134 P. Burtscher et al J. Endo 17:10 1991

135 E. Pissiotis et al J. Endo 17:5 1991

136 S. Inoue et al J. Endo 17:8 1991

137 T. Coen et al J. Endo 18:3 1992

138 D. Smith et al J. Endo 18:1 1992

139 P. Abbott et al J. Endo 18:11 1992

140 J. Smith et al J. Endo 18:4 1992

141 W. Wong et al J. Endo 20:12 1994

142 P. Randolph et al J. Endo 21:2 1995

143 M. Torabinejad et al J. Endo 21:3 1995

144 F. Goldberg et al J. Endo 21:10 1995

145 J. Welch et al J. Endo 22:11 1996

146 N Hosoya et al J. Endo 21:9 1995

147 F Gerhards et al J. Endo 22:9 1996

148 C. Lee et al J. Endo 23:4 1997

149 The American Association of Endodontists (http://www.aae.org):
"Facts About Root Canal Treatment and Endodontists

150 Caulk Co 1998
In proximal or occlusal contact to dissimilar metal restorations.
In patients with severe renal deficiency.
In patients with known allergies to amalgam.
For retrograde or endodontic filling.
As a filling material for a cast crown.
In children 6 and under.
In expectant mothers.

151 http://www.aae.org)

152 the Canadian Academy of Endodontics claim that;

153 "The Changing Face Of Dentistry - Endodontics" by Dr Paul V. Abbott BDSc, MDS, FRACDS(Endo). Australian Dental Association News Bulletin April 1996

154 Endodontic treatment and general health April 1996 A recent press report (Daily Mail, April 9 1996) suggested that the removal of endodontically-treated teeth could alleviate various health conditions, including arthritis and kidney and heart disease.

155 http://www.ase.org.au/media/Societies/ASE/Documents/Endontics%20Can%20Save%20That%20Tootha.pdf

156 12 April 1997
Dr Ralph Reid
12th Floor
TNG Building
141 Queen St
Brisbane
4000

Dear Dr Reid,
I am writing with a request for information which I hope you, as president of the Australian Society of Endodontology (Inc.), will be able to supply. I am a practicing general dentist in Sydney and have a great interest in the area of Endodontics. My queries are in relation to the patient education pamphlet;
"Relax- there is no need to lose your tooth…ENDODONTICS (Root Canal Therapy) can save it for you".

1) In paragraph 2 it is written "Once the tooth is fully formed the main source of nutrition for the tooth comes from the tissues surrounding the root."
Could you please supply the references for this statement? Would you also be kind enough to explain to me exactly how the tooth is nourished from its surrounding tissues. Is this via the blood supply, the lymph or by osmosis?

Interestingly the American Dental Association state in 2005 on their web site
"Inside each tooth is the pulp which provides nutrients and nerves to the tooth, it runs like a thread down through the root."
American Dental Association Web site Jan 2005 http://www.ada.org/public/topics/root_canal.asp

2) In the third paragraph it is written;
"Therefore, a tooth can function normally without its pulp and can be kept indefinitely. After endodontic treatment the tooth is pulpless, but it is NOT a dead tooth."
Again I would appreciate references to support this statement. By suggesting that the tooth is not dead, one can only assume that it is alive. For this to be so it must have some vascular supply. If I am not mistaken the very procedure of Root Canal Therapy is to remove the blood supply.

The statement (7th Paragraph) "During endodontic treatment, the infected or damaged pulp is removed from the inside (i.e. root canal) of your tooth."
Is it necessary to remove all infected dead pulp tissue from the tooth? If not please supply references which describe the fate and effect of remaining infected tissue.
If so please supply the references which demonstrate that all necrotic and infected tissue can be removed from the tooth.

The 8th Paragraph states: "The root canals are then cleaned, sterilised and shaped to a form that can be completely sealed." Firstly I again request references to support this statement. Next would you be kind enough to explain to me;
the procedure and medication recommended by the society which does sterilise a tooth.
how is sterility of the tooth determined? Is it necessary to take a swab of the tooth for culturing. If so should this be aerobic or anaerobic.
if anaerobic testing is required could you please inform me of the correct procedures.
please supply references which demonstrate the complete sealing of a root canal.

Paragraph 11 talks of the sedative dressings and temporary fillings which are used to settle the tooth "and destroy any remaining bacteria" . References supporting this statement would be appreciated. Would you also list for me the medicaments which are currently recommended to achieve this outcome.

They also talk about dressings which "and destroy any remaining bacteria"

I appreciate that you may not be the author of this pamphlet and that this is indeed quite a large request. I believe though, that if I am to pass this pamphlet on to my patients, I would like to be in a position to be able to verify each of these statements by published, peer reviewed scientific papers.

If you are unable to furnish the answers to this request I would appreciate it if you could point me to the author of this paper. I thank you in advance for your response.

Yours sincerely Robert Gammal

***************
Following is their response.

Dear Dr Gammal,

Thank you for your original letter of the 12th April. The request was handed on to our committee which handles educational matters. I have just returned from three weeks away, hence the delay in replying
The committee made the following recommendations which are passed on for your Information:
The pamphlet was written by a committee of specialist endodontists as a public service to dentist's patients.
The pamphlet was then circulated to all specialist endodontists in Australia for their comments, additions, etc before final printing.
The material was based on the committee members' general knowledge of endodontics and not on specific references.
The statements are universally accepted by endodontists world-wide and by the dental Profession in general.
There are no controversial issues raised in the pamphlets (this was intentionally avoided by the committee)
NO specific references were used to write the pamphlets
ANY textbook on endodontics could be used to justify the statements made in the pamphlets.

I hope this information is of some help in showing where the pamphlets have come from.
Yours sincerely Ralph J Reid. President, ASE Inc (Bold emphasis by Robert Gammal )


157 :"Transatlantic Transfer of Digitized Antigen Signal by Telephone Link," J. Benveniste, P. Jurgens, W. Hsueh and J. Aissa, "Journal of Allergy & Clinical Immunology - Program and abstracts of papers to be presented during scientific sessions AAAAI/AAI.CIS Joint Meeting February 21-26, 1997"]


158 California PROPOSITION 65:
Warning on dental amalgam, used in many dental fillings, causes exposure to mercury, a chemical known to the state of California to cause birth defects or other reproductive harm.

Root canal treatments and restorations including fillings, crowns and bridges, use chemicals known to the state of California to cause cancer.

159 Dental Infections - Oral and Systemic Being a contribution to the Pathology of Dental Infections, Focal infections and the Degenerative Disseases. Weston A Price DDS., MS., FACD Cleveland Ohio The Penton Press Co Cleveland 1923

160 Charlton BR Channing-Santiago SE Bickford AA Cardona CJ Chin RP Cooper GL Droual R Jeffrey JS Meteyer CU Shivaprasad HL et al Preliminary

161 characterization of a pleomorphic gram-negative rod associated with avian respiratory disease. J Vet Diagn Invest (1993 Jan) 5(1):47-51

162 Cantwell AR Variably acid-fast pleomorphic bacteria as a possible cause of mycosis fungoides. A report of a necropsied case and two living patients J Dermatol Surg Oncol (1982) 8(3):203-213

163 Cantwell AR Lawson JW Necroscopic Findings Of Pleomorphic, Variably Acid-Fast Bacteria In A Fatal Case Of Kaposi's Sarcoma J Dermatol Surg Oncol (1981) 7(11):923-930

164 Eisenberg RJ Montgomery PC Characterization of an antibody directed against a surface component of normal and pleomorphic cells of Streptococcus sanguis. Infect Immun (1975 Sep) 12(3):668-78

165 Maeda N Anaerobic, gram-positive, pleomorphic rods in human gingival crevice.
Bull Tokyo Med Dent Univ (1980 Mar) 27(1):63-70

166 Ishikawa O Aerobic gram-positive pleomorphic rods isolated from dental plaque
and gingival crevice. Bull Tokyo Med Dent Univ (1980 Mar) 27(1):71-7

167 Bauld J Marshall KC Quantitative description of morphological changes during growth of a pleomorphic budding bacterium. Antonie Van Leeuwenhoek (1971) 37(4):401-7

168 Wainwright M Highly pleomorphic staphylococci as a cause of cancer. Med Hypotheses (2000 Jan) 54(1):91-4


169 Journal of the American Dental Association Vol 42 June 1951(619-633)
170 J of Endodontics Vol3 No 5 May 1976

171 Hubert Newman Focal infection Dent Res 75 (12) 1996 t Newman Focal infection Dent Res 75 (12) 1996 edited by Irwin Mandel (Assoc. Dean for Research School of Dental and Oral Surgery Colombia University New York )

172 Walsh LJ Serious complications of endodontic infections: some cautionary tales.
Aust Dent J (1997 Jun) 42(3):156-9 ISSN: 0045-0421

173 N. Tani et al J. Endo 18:2 1992 A wide range of pathobiological properties are attributed to the most frequently isolated endodontic pathogens

174 Siskin M Oral Surg. 1977 Vol 43 No 3 Various immunologic diseases may be associated with Pulpal-Periapical Disease

175 Rubin et al Oral Surg 1976 Vol 41 No 1 Three cases of infection of total hip replacements following Root Canal Therapy in 2 cases and Periodontal Surgery in 1 case.

176 J Am Dent Assoc 1995 Apr;126(4):469-72; quiz 499-500 Abscess involving the left eye that originated as a dental abscess

177 J Oral Maxillofac Surg 1995 Feb;53(2):203-8 1995 Feb Cervical cellulitis and mediastinitis caused by odontogenic infections

178 Rapoport Y et al Oral Surg Oral Med Oral Pathol 1991 Jul;72(1):15-8 Cervical necrotizing fasciitis of odontogenic origin

179 Mattila KJ et al Atherosclerosis 1993 Nov;103(2):205-11 Dental infections and coronary atherosclerosis

180 J Am Dent Assoc (1989 Sep) 119(3):397-8, 401-2 Infection of pulpally involved teeth near the maxillary sinus sometimes spreads into the sinus and causes serious complications

181 Steiner G J Neuropath. 1952;11:343-72 Support for the Oral Spirochaetes theory relating MS to oral infections

182 Eliezer et al Oral Surg June 1978 Vol 45 No 6 Brain Abscess following Dental Infection

183 Valachovic R Hargreaves JA Oral Surg Oral Med Oral Pathol (1979 Dec) 48(6):495-500

184 Perna E et al. "Actinomycotic Granuloma of the Gasserian Ganglion with primary site in a dental root" J of Neurosurg 54 (1981) 553-555 Some brain cancers can be caused by infection in a tooth

185 Black R., laboratory model for Trigeminal Neuralgia. Adv. Neuro.1974; 4:651-8 There is now evidence of demyelenation of the Gasserian Ganglion after damage as far away as a tooth pulp

186 Westrum LE., Canfield RC., Black R., Transganglionic Degeneration in the spinal trigeminal nucleus following the removal of tooth pulps in adult cats.
Brain Res 1976; 6:100:137-40

187 Westrum LE., Canfield RC., Electron microscopy of degenerating axons and terminals in the spinal trigeminal nucleus after tooth pulp exterpation.
Am J Anat. 1977; 149:591-6

188 Gobel S., Bink J., degenerative changes in primary trigeminal axons and in neurons in nucleus caudalis following tooth pulp extirpation in the cat., :
Brain Res. 1977;132:347-54

189 Mucke L Clinical management of neuropathic pain Neurol clin 1987;5:649-63

190 Fromm G., et al Trigeminal Neuralgia. Current concepts regarding etiology and pathogenisis Arch Neurol 1984;41: 1204-7

191 Bayer D. et al Trigeminal Neuralgia an overview. Oral Surg. Oral Med. Oral Pathol. 1979:48:393-9

192 Selby G., Diseases of the fifth cranial nerve. In Dyke PJ., Thomas PK.,

193 Peripheral Neuropathy. Philadelphia. W.B. Saunders 1984;1224-65

194 King R. Interaction of noxious and nonnoxious stimuli in primary sensory nuclei Adv Neurol 1974; 4:659-63

195 Meurman JH Dental infections and general health. Quintessence Int (1997 Dec) 28(12):807-11

196 Stortebecker P "Dental Infectious Foci and diseases of the nervous system - spread of microorganisms and their products from dental infectious foci along direct cranial venous pathways eliciting a toxic - infectious encephalopathy" Acta. Psych Neural Scand 36 Suppl. 157 (1961) 62

197 Stortebecker P "The cranial venous system filled from pulp of a tooth - Proceedings" 3rd Int. Congress of Nero Surg. Copenhagen Aug 1965

198 Stortebecker P "Dental significance of pathways for dissemination from infectious foci." J Can Dent Assoc 33:6 1967 pp301-311

199 Stortebecker P "Chronic dental infections in the etiology of Glioblastomas. 8th int congress" Neuropathy. Washington D.C. Sept 1978 J Neuropth. Exp. Neurology 37(s) 1978

200 Selden HS The endo-antral syndrome: an endodontic complication. J Am Dent Assoc (1989 Sep) 119(3):397-8, 401-2

201 Ngeow WC Orbital cellulitis as a sole symptom of odontogenic infection. Singapore Med J (1999 Feb) 40(2):101-3

202 Maloney PL Doku HC Maxillary sinusitis of odontogenic origin. J Can Dent Assoc (1968 Nov) 34(11):591-603

203 Guglani L Maxillary sinusitis due to dental infection. Newsl Int Coll Dent India Sect (1970 Sep) 7(3):15

204 Yamazaki Y Shimada K Sakuma M Kawashima Y Kobayashi H [Odontogenic maxillary sinusitis: with special reference to surgical therapy] Nippon Jibiinkoka Gakkai Kaiho (1972 Oct) 75(10):1125-6

205 Esposito S [Maxillary sinusitis of dental origin] Rass Int Clin Ter ( 1970 Jan 15) 50(1):39-45

206 Azimov M Ermakova FB [Role of focal odontogenic infection in the pathogenesis of maxillary sinusitis (experimental study)] Stomatologiia ( Mosk) (1978 Jan-Feb) 57(1):11-4

207 Neupokoev NI Neupokoeva NV [Periapical cyst of the maxillary teeth as a cause of odontogenic maxillary sinusitis] Stomatologiia (Mosk) (1991 May-Jun) 70(3):62-3

208 Bertrand B Rombaux P Eloy P Reychler H Sinusitis of dental origin. Acta Otorhinolaryngol Belg (1997) 51(4):315-22

209 Stefaniu A Czausescu V Popescu N Romascanu G Ceausescu A [Orbito- ocular and meningoencephalic complications in odontogenic maxillary sinusitis] Rev Chir Oncol Radiol O R L Oftalmol Stomatol Otorinolaringol ( 1982 Jan-Mar) 27(1):59-64

210 Tarlowska W A case of chronic inflammation of the right maxillary sinus caused by the introduction of cement into its lumen during root canal treatment of the 1st molar through the palatal root canal Czas Stomatol (1968 Jan) 21(1):25-8

211 Sato K Pathology of recent odontogenic maxillary sinusitis and the
usefulness of endoscopic sinus surgery Nippon Jibiinkoka Gakkai Kaiho (2001 Jul) 104(7):715-20

212 Selden HS The interrelationship between the maxillary sinus and endodontics.
Oral Surg Oral Med Oral Pathol (1974 Oct) 38(4):623-9

213 Selden HS August DS Maxillary sinus involvement--an endodontic complication. Report of a case. Oral Surg Oral Med Oral Pathol (1970 Jul) 30(1):117-22

214 Thevoz F Arza A Jaques B Dental foreign body sinusitis Schweiz Med Wochenschr (2000) Suppl 125:30S-34S

215 Bogaerts P Hanssens JF Siquet JP Healing of maxillary sinusitis of odontogenic origin following conservative endodontic retreatment: case reports. Acta Otorhinolaryngol Belg (2003) 57(1):91-7

216 Gay D Dick G Is multiple sclerosis caused by an oral spirochaete? Lancet (1986 Jul 12) 2(8498):75-7

217 Callaghan TS Multiple sclerosis and sinusitis Lancet (1986 Jul 19) 2(8499):160-1

218 Gay D Dick G Upton G Multiple sclerosis associated with sinusitis: case-controlled study
in general practice. Lancet (1986 Apr 12) 1(8485):815-9

219 Jones RL Crowe P Chavda SV Pahor AL
The incidence of sinusitis in patients with multiple sclerosis. Rhinology (1997 Sep) 35(3):118-9 A retrospective study was performed to assess the incidence of sinus disease in patients with MS.

220 Symons AL Bortolanza M Godden S Seymour G A preliminary study into the dental health status of multiple sclerosis patients. Spec Care Dentist (1993 May-Jun) 13(3):96-101

221 Khmel'nik VM [Combined intracranial complication in chronic odontogenic maxillary sinusitis] Kombinirovannoe vnutricherepnoe oslozhnenie pri khronicheskom odontogennom gaimorite. Vestn Otorinolaringol (1981 May-Jun)(3):87-8 ISSN: 0042-4668

222 Craelius W Comparative epidemiology of multiple sclerosis and dental caries. J Epidemiol Community Health (1978 Sep) 32(3):155-65

223 Peter Dosch MD - Manual of Neural Therapy according to Huneke

224 Professor Otto Neuner Biological Therapy Vol VI No2 April 1988

225 Peter Dosch MD Facts about Neural Therapy according to Huneke 20th German edition Haug Publishers ISBN 3-7760-0851-2 1985

226 Mathias Dosch MD Illustrated Atlas of the Techniques of Neural Therapy with Local Anesthetics Haug publishers ISBN 3-7760-0849-0 1985

227 Ernesto Adler MD DDS Neural Focal Dentistry 2nd Edition 1984 Multi-Discipline Research Foundation 6550 Tarnef Houston, Texas 77074

229 R.Steinman J Dent Res St. Louis, Vol 37 #5 1958

230 R.Steinman J Dent Res St. Louis, Vol 37 #4 1958

231 R.Steinman Indiana State Dental Journal Vol 39 1960

232 R.Steinman J Southern California State Dental Assoc. Vol 28, No11 November 1960

233 R.Steinman J of Southern California State Dental Association Vol 29 1961

234 R.Steinman J of Southern California State Dental Association Vol 30 1962

235 R.Steinman J of Southern California State Dental Association Vol 31 1963

236 R.Steinman J of Southern California State Dental Association Vol 32 1964

237 R.Steinman Caries and Cellular Nutrition, Dental Progress Vol.2; #3 April 1962

238 R.Steinman J Southern California State Dental Assoc. Vol 35 No 4 April 1967

239 R. Steinman J. Dent Res. Vol 47, No5, Sept 1968

240 R. Steinman J. Dent Res. Vol 50, No6, Part 2. Nov-Dec 1971

241 Aars H Gazelius B Edwall L Olgart L Effects of autonomic reflexes on tooth pulp blood flow in man. Acta Physiol Scand (1992 Dec) 146(4)

242 R Steinman Dental Progress Vol 2 1962 Abstracts of Steinman p42 International Academy of Microendocrinology

243 Danielson, C.; Lyon, J.L.; Egger, M.; Goodenough, G.K. Hip fractures and fluoridation in Utah's elderly population- Journal of the American Medical Association. 258:746748,1992.

244 Hip Fracture rates related to Fluoridated water Journal of the American Medical Association 264(4):500-502 1990

245 J. C. Robins and J. L. Ambrus, "Studies on Osteoporosis IX. Effect of Fluoride on Steroid Induced Osteoporosis," Research Communications in Chemical Pathology and Pharmacology, Volume 37, No. 3, pp. 453-461 (1982)

246 McIvor, M., et al. Hyperkalemia and cardiac arrest from fluoride exposure during hemodialysis. American Journal of Cardiology. 51: 901-902, 1983.

247 Fluoride blamed for death. Ketchikan, Alaska Daily News, June 1, 1998.

248 Machoy-Mokrzynska, A. Fluoride-magnesium interactions- Fluoride. 28(4):175, November 1995.

249 Carcinogenesis, Vol. 9, pp. 2279-2284 (1988)

250 Sodium Fluoride: individual animal tumor pathology table [rats], Battelle Memorial Institute, February 23, 1989

251 Sodium Fluoride: individual animal tumor pathology table [mice], Battelle Memorial Institute, April 11, 1989

252 Dr. Wm Marcus May Day Memo discussed in Lancet 36, page 737 (1990)

253 Review of Fluoride: Benefits and Risks, U. S. Public Health Service, pp. F1-F7 ( 1991)
Fluoride Vol. 26, pp. 83-96 (1992) Fluoride is an equivocal carcinogen

254 A Brief Report on the Association of Drinking Water Fluoridation and the Incidence of Osteosarcoma among Young Males, New Jersey Department of Health, November 1992

255 Freni SC, Journal of Toxicology and Environmental Health, 42:109-121, 1994

256 Li, X.S.; Zhi, J.L.; Gao, R.O. Effect of fluoride exposure on intelligence of children. Fluoride. 28(4):189-192,1995.

257 Diesendorf M. Tooth Decay not related to fluoride intake from water Nature Vol. 322 10 July 1986

258 Colquhoun J. Tooth Decay related to economics of family American Laboratory 17:98-109 1985

259 Colquhoun J. Community Dentistry and Oral Epidemiology 13:37-41 1985

260 Dr. John Yiamouyiannis statement both in his book (Fluoride the Aging Factor" pub Health Action Press 2nd ed. 1986 )and during debates has not been challenged by the ADA or others.
Ziegelbecker D. Fluoride 14; 123-128 1981

261 Cancer - A second Opinion by Josef Issels MD Avery Publishing Group ISBN 0-89529-992-5 1999
----------
262 Mattman L "Cell Wall Deficient Forms : Stealth Pathogens" 2nd Ed. CRC Press Boca Raton 1992 pg 9.

263 Enby E., Gosch P, Sheehan M. "Hidden Killers - The Revolutionary Medical discoveries of Professor Guenther Enderlein" Sheehan communications Saratoga CA 1990 pg12

264 Butlin, Henry T., "Malignant Tumours and Parasitism" British Medical Journal, Vol 1. 1884
Doyen T.A. "The aetiology and treatment of cancer." Edinburgh Med.J. 1905; 17:373-378

265 Glover TJ., Engle JL., Clark GA., Leffler HH., "Former Investigations into the Microbic Origin of Cancer" Report to United States government at conclusion of Washington work.

266 Nuzum, J.W. "The Experimental production of metastasising carcinoma in the breast of the dog and primary epithelioma in man by repeated inoculation of a Micrococcus isolated from human breast cancer" Surg.Gynecol.Obstet.,11/343-352. 1925
Glover T.J. "The bacteriology of cancer" Can. Lancet Pract., 75, 92-111, 1930

267 Clark GA "Successful Culturing of Glover's Cancer Organism and Development of Metastasizing Tumours in Animals Produced by Cultures from Human Malignancy." Presentation at Sixth International congress of Microbiology; Rome, Italy, September 1953

268 Brehmer W. "Siphonospora polymorphs: n.sp., ein neuer Mikroorganismus des Blutes und seine Beziehung zur Turmorgenese: Med. Welt, 8, 1179-1185, 1934

269 Gerlach F. "Erorterung des Krebsproblems vom Standpuckt der Bakteriologie (Discussion of the cancer problem from the point of view of bacteriology). Mikroskopie Nos. 1 & 2, 1952

270 Gerlach F. "Immunbiologische Studien bei malign Tumoren und Hamoblastosen (Immunlogical studies of maligant tumours and hemoblastoses) Der Krebsarzt No. 2, 1961

271 Gregory, JE. "Pathogenesis of Cancer" 3rd ed., Premont foundation Publishers, Pasadena, CA, 1955

272 Villequez, E. "Le parasitism latent des cellules du sang chez l'homme, en particulier dans le sang des cancereux" Librairie Maloine, Paris 1955

273 Fonti C.j., "Etiopatogeneses del Cancro: Diagnosis, Prophylaxis Therapy" Kndustrie Grafiche, A. Nicola and co., Milan-Varese
Cantwell A. "Four Wojmena Against Cancer" Aries Rising Press, Los Angeles 2005 pg34

2714 Cantwell A "Four Women Against Cancer" Aries Rising Press, Los Angeles, 2005 pg 38

275 Wuerthele-Caspé et al "Cultural Properties and pathogenicity of certain Microorganisms obtained from various proliferative and neoplastic diseases" American Journal Medical Sciences, 220, 638-648, Dec. 1950

276 Alexander-Jackson E. " Mycoplasma (PPLO) Isolated from Rout Sarcoma Virus" Growth 1966, 30: 199-228

277 Livingston VWC, Alexander-Jackson, E "A specific type of organism cultivated from malignancy, bacteriology and proposed classification: Ann. N.Y Acad.Sci.,174, 636-654, 1970

278 Livingston VWC, Livingston AM "Demonstration of Progenitor cryptocides in the blood of patients with collagen and neoplastic diseases" Trans. N.Y. Acad. Sci 34, 433-453, 1972

279 Livingston-Wheeler, VWC, "Compendium - The microbiology of Cancer" Livingston wheeler Medical Clinic Publication, US 1977 pg 13

280 Cantwell A.R.Jr. "Histologic observations of variably acid fast coccoid forms suggestive of CWD bacteria in Hodgkins disease, 4 cases" Growth, 45, 168-187, 1981

281 Cantwell A.R.Jr. "Variably Acid-fast Bacteria in a Rare Case of Coexistent Malignant Lymphoma and cutaneous Sarcoid-like Granulomas" International Journal of Dermatology," March 1982, Vol 21, No 2

282 Cantwell A.R.Jr. "The cancer microbe" Intern J. Med 1997; Vol 1, 7.-15

283 Mattman L.H. "Cell Wall Deficient Forms - Stealth Pathogens" 2nd Ed. CRC Press, 1992 Boca Raton pg

More information at   www.robertgammal.com

created by La Mmag

It is true that the grasping of truth is not possible without empirical basis.  However, the deeper we penetrate and the more extensive and embracing our theories become, the less empirical knowledge is needed
to determine those theories 

Albert Einstein 1952